"You take the good, you take the bad ... ." Originally set at the prestigious Eastland School for Young Women, housemother Mrs. Garrett is the caretaker and confidante of a special group of girls. Over time, this group shrinks to be centered on only four young women: wealthy and spoiled Blair, gossipy Tootie, eager-to-please Natalie and tough girl Jo. Over the years, the girls graduate from school, and the story lines evolve with them.