During the Spanish-American War, the plague of yellow fever ravaging Cuba leads the U.S. Army to send a team of doctors, led by Maj. Walter Reed (Lewis Stone), to beat the disease. As Reed and his team search for the cause of yellow fever, they realize that they'll need to run life-threatening experiments on humans in order to find a cure. American soldiers Jellybeans (Buddy Ebsen), O'Hara (Robert Montgomery) and Breen (William Henry) valiantly volunteer to be Reed's test subjects.
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