Frank Mayo made some of Universal's best program features; here he receives support from lovely newcomers Lillian Rich and Mary Philbin. Bradley Yates (Mayo) works so intently on discovering a new blood serum that it gives him a nervous breakdown. His associate, Dr. Pickney Forbes (Frank Holland), sends him to the Blue Ridge mountains for a rest. Yates goes by an assumed name, Pickins, and is accepted by the rural folk as a woodsman. Talithy Millicuddy (Philbin), the innocent daughter of a shopkeeper (Bert Sprotte), falls in love with him when he gives her some books and takes a brotherly interest in her. The woman Forbes prefers is Carroll Brown, the new school teacher (Rich). Talithy persists in pursuing Forbes, and the mountain people turn against him. But his spirit has returned and he finishes his work on the serum, which saves Carroll's life when she is stricken with blood poisoning. When she recovers, Carroll and Forbes become engaged.
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