Bob (Gordon Griffith), John, and Edward all grow up in the same neighborhood. John and Edward are neglected by their parents, but Bob's father (Edward Cecil) takes him aside to lecture him about life and sex. He even takes him to the hospital -- not to the maternity ward, of course, but to the ward where men are being treated for various sexual diseases. Bob learns his lesson and grows up (to be played by Jack Mulhall) and becomes engaged. His pals also have sweethearts, but they come to tragic ends. John (as an adult played by Leo Pierson) contracts syphilis and goes to a quack doctor to cure it. The treatment is not successful and he is forbidden to marry. Edward goes insane from self-abuse. After engaging in criminal activity, he is arrested and declared to be mentally incompetent. Bob is the only one who escapes these dire fates and the film's final frames show him to be very happily married.
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