Carefree young scientist Chris Claybourne (Robert Taylor) follows his esteemed father's footsteps into the demanding field of epidemiology. Before embarking on his first research expedition, Claybourne obtains permission to go on a brief vacation. In the midst of a fierce gambling binge, Claybourne falls for seductive model Rita Wilson (Barbara Stanwyck) and gets deeply in debt to a local gangster. When Claybourne appeals to his brother Tom (John Eldredge) for help, a love triangle ensues.
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