Episode Five of the Pathe serial Hands Up finds plucky girl reporter Echo Delane (Ruth Roland) still at large in South America. Having been designated as the reincarnated queen of the Incan nation, Echo has also been targeted for a forced marriage and a human sacrifice. She is rescued at every turn by the mysterious Phantom Rider, who may or may not be nominal hero "Hands-Up" (George Cheseboro). But Echo is no damsel in distress, and she manages to wriggle out of many a predicament by herself. Secretly undercutting her survival efforts is her treacherous cousin Judith (Easter Walters), who will come into Echo's inheritance should the heroine meet with an "accident."
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