Mad scientist Dr. Kurt Leopold (Marshall Grauer) has developed a formula that can transform a human into a giant creature that looks like a catfish. Laughed out of the medical establishment, he seeks revenge by using the serum on himself and killing two of his former colleagues. He then decides to seek out a mate and abducts scientist Martha Walsh (Sanna Ringhaver), wanting to transform her with his serum. Meanwhile, Sheriff Lou Krantz (Paul Galloway) tries to save her.
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