In 1870s Transylvania, scientist Dr. Callistratus (Donald Wolfit) is put to death by villagers who wrongly believe he's a vampire. However, his horribly disfigured henchman, Carl (Victor Maddern), is on hand to orchestrate a life-saving heart transplant. Revived, Dr. Callistratus makes his way to a remote asylum, which he manages to assume control of. But, realizing the operation he underwent has left him with a constant need for blood, the mad doctor looks to his patients for a fresh supply.
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