In a series of vignettes that serve as a sequel to Amici Miei, director Mario Monicelli brings back several of his stars from the earlier movie to continue their antics in Florence, home of the friends of the title. All five are (or in some cases, were) close companions and have a penchant for practical jokes. Count Lello Mascetti (Ugo Tognazzi) may not have much money, but then he has an unattractive, pregnant, unmarried daughter to compensate. Prof. Sassaroli (Adolfo Celi) is a surgeon who decides to get back at a slightly senile loan shark, and the other friends range from a bar owner to a love-sick man. Together, they are sure to go from one unlikely situation to the next.
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